Crosslinking Reagents
Medchemexpress LLC Hexanoic acid, 6-azido-, 2,5-dioxo-1-pyrrolidinyl ester | 866363-70-4 | MFCD25968077 | ≥98.0% | 254.24 g/mol | C10H14N4O4 | 1 G
N3-C5-NHS ester is an azide-functionalized N-hydroxysuccinimide (NHS) ester used as a noncleavable ADC linker and a click-chemistry reagent for bioconjugation. It enables coupling to primary amines via NHS chemistry and to alkynes via azide-alkyne cycloaddition reactions, and is supplied as a colorless to light yellow liquid with high purity.
- Noncleavable ADC linker suitable for antibody-drug conjugation
- Enables conjugation to primary amines via NHS ester chemistry
- Compatible with copper-catalyzed and strain-promoted azide-alkyne click reactions
- Azide functionality provides orthogonal bioconjugation options
- Supplied as a 1 g quantity for laboratory use
Lumiprobe Sulfo-Cyanine5 NHS ester | 2230212-27-6 | MFCD30527435 | 25 mg
Sulfo-Cyanine5 NHS ester | Purity: 95% | Mol Wt: 777.95 | 2230212-27-6 | MFCD30527435 | 25 mg
Broadpharm Sulfo-NHS | 106627-54-7 | MFCD00043100 | 1g
Sulfo-NHS | Putity: 97% | MW: 217.1 | 106627-54-7 | MFCD00043100 | 1g
Cayman Chemical Aceclofenac methyl ester 50mg
A potential impurity in commercial preparations of aceclofenac; has been used as a precursor in the synthesis of aceclofenac
Cayman Chemical TazarotenIc AcId 50mg
An RAR agonist and an active metabolite of tazarotene; induces reporter gene expression in DK7-NR cells expressing human RARα, RARβ, or RARγ (EC50s = 11, 2.5, and 11 nM, respectively); reduces EAr edema in a PMA-induced mouse model of epidermal inflammation when applied topically at 0.1% w/w
Medchemexpress LLC Propargyl-C2-NHS ester | 906564-59-8 | 97.0% | 209.20 g/mol | C10H11NO4 | 500 MG
Propargyl-C2-NHS ester is a non-cleavable linker and click-chemistry reagent used for antibody-drug conjugation and general bioconjugation. It features an alkyne (propargyl) moiety for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and an N-hydroxysuccinimide (NHS) ester for efficient amine coupling.
- Molecular formula: C10H11NO4
- Molecular weight: 209.20 g/mol
- Purity: 97.0%
- Physical form: Colorless to off-white, solid/liquid mixture
- Solubility: 100 mg/mL in DMSO
- Storage: pure form -20°C (3 years); in solvent -80°C (6 months)
- Applications: antibody-drug conjugation and general bioconjugation
Medchemexpress LLC N3-C4-NHS ester | 478801-48-8 | 99.5% | 240.22 g/mol | C9H12N4O4 | 250 MG
N3-C4-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker and click-chemistry reagent containing an azide group. It is used for bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), and is suitable for ADC synthesis and related chemical biology applications. Purity is 99.53%, molecular weight 240.22 g/mol, formula C9H12N4O4. Storage: pure form -20°C for long-term stability.
- Noncleavable ADC linker for antibody-drug conjugate synthesis.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN.
- High purity: 99.5% to support sensitive conjugation reactions.
- Stored at -20°C in pure form for up to 3 years.
Cayman Chemical Sulfo-SMCCsodIum salt 100mg
A water-soluble protein cross-linking reagent; has been used to conjugate anti-PD-L1 antibodies to the surface of platelets and Golgi-targeting peptides to platelet microparticle-mimetic nanoplatforms
Cayman Chemical Halobetasol PropIonate 10mg
A synthetic glucocorticoid; inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 UG/animal) and by oxazolone in mice (ED50 = 0.8 UG/animal); has anti-inflammatory effects on croton oil-induced EAr edema in rats (ED50s = 10 UG/ml and 0.5 UG/ear) and mice (ED50s = 1.2 and <0.32 UG/ear after 6 and 24 hours of treatment, respectively)
Cayman Chemical HomogentIsIc AcId 50mg
An intermediate in the catabolism of aromatic amino acids; formed in excess during alkaptonuria
Medchemexpress LLC DSG-PEG (MW 2000) | 308805-39-2 | 100.0% | 2000 Da (average) | C130H258O50 (average) | 50 MG
DSG-PEG (average MW 2000 Da) is a PEGylated lipid supplied as a high-purity solid for use in liposome and lipid nanoparticle formulation. It provides a methoxy-PEG chain anchored to a distearoyl glycerol lipid to incorporate into bilayers and modify surface properties.
- Provides steric stabilization to liposomes and lipid nanoparticles.
- Incorporates into lipid bilayers via a distearoyl glycerol anchor.
- Average PEG molecular weight ~2000 Da for controlled hydration layer.
- High purity solid suitable for research-scale formulation.
- Compatible with common solvents used in lipid film hydration and nanoparticle assembly.
- Powder storage at -20°C preserves stability for long-term storage.